Research from the Columbus Lab featured on cover of JACS

Opa proteins are outer membrane proteins in Neisseria meningitidis and Neisseria gonorrhoeae that have flexible extracelullar loops that interact with human receptors. This Opa-receptor interaction triggers the engulfment of the bacterium by human host cells. The cover shows several conformers of these loops extending from the Opa β-barrel which is embedded in a lipid bilayer. […]

Ryan Lo and Ryan Oliver are now Dr. Lo and Dr. Oliver

On May 18, 2014, Ryan Oliver and Ryan Lo received their PhD at the Chemistry Graduation Ceremony. They successfully defended their theses earlier in the Spring semester. Dr. Ryan Lo’s thesis entitled “Spectroscopic Studies of Membrane Protein Structure, Dynamics, and Function” focused on investigations of Opa proteins involved in the engulfment of Neisseria gonorrhoeae. Dr. […]

Nana, Shelby, Jessica, and Sebastien Receive Undergraduate Summer Fellowships

All four undergraduates in the Columbus Laboratory received 2014 Summer Research Fellowships. Nana and Shelby received a Bass Scholarship from the Chemistry Department. Sebastien received a a 2014 nanoSTAR Undergraduate Summer Research Award. Jessica Yoo received a a 2014 CSS Summer Research Stipend.

Jen Presents a Poster at the Protein Transport Across Cell Membranes Gordon Research Conference

Jen presented a poster entitled “Neisseria Opa protein interactions with human receptors in vitro and in vivo” at the Protein Transport Across Cell Membranes Gordon Research Conference in Gavelston Texas on March 9-14, 2014. The poster described her thesis work in collaboration with the Criss laboratory.

Tsega receives 2014 Dolphus E. Milligan Fellowship

Tsega was accepted into the University of Maryland, College Park Chemistry and Biochemistry PhD program. She received the 2014 Dolphus E. Milligan Fellowship Award through a competitive process that included a 30 minute oral presentation. The award includes a two-year research assistant fellowship and a summer internship at the National Institute of Standards and Technology […]

Ashton Brock and Ryan Lo present at the 58th Annual Meeting of the Biophysical Society

Linda, Ryan, and Ashton attended the 58th Annual Meeting of the Biophysical Society in San Francisco on February 15 – 19, 2014 Ryan presented a poster entitled “Structure, dynamics and receptor binding of Opa proteins” on Monday afternoons poster session. Ashton presented a platform talk entitled “Influence of detergent properties on the solubilization and purification […]

Linda receives the Virginia Outstanding Faculty Award

The Outstanding Faculty Awards are the Commonwealth’s highest honor for faculty at Virginia’s public and private colleges and universities. These awards recognize superior accomplishments in teaching, research, and public service. See the articles in UVA Today and Cavalier Daily.

Columbus Lab Undergraduates Present at SURC 2014

On Thursday, January 30th, The Columbus Lab undergraduates drove to the University of Tennessee in Knoxville to attend the 46th Southeast Undergraduate Research Conference. Graduate students, Ashton Brock and Jennifer Martin and Linda joined them for the adventure. Nana Bosomtwe presented a poster entitled Thermophilic Coupling Enzymes: Enabling Functional Studies at Physiological Temperatures and was […]

Lab Celebrates Tenure at Snowshoe

A few years ago, Linda signed a document that said if she earned tenure she would bring the lab on a ski trip. In August, Linda was tenured so we headed to Snowshoe, WV on December 13th, 2013. Brett, Michelle, and Ingrid came from Nashville, TN and Alison and Georgine came from Salisbury, MD and […]