Columbus L, Lipfert J, Jambunathan K, Fox DA, Sim AYL, Doniach S, and Lesley SA. Mixing and Matching Detergents for Membrane Protein NMR Structure Determination J. Am. Chem. Soc. 131:7320–7326 (2009)
Dan Fox
Dan and Linda contribute to CIL’s Biomolecular NMR Product Catalog.
The new Cambridge Isotope Laboratories, Inc. Biomolecular NMR Product Catalog has pieces written by various NMR spectroscopists that utilize their isotopes. Dan adn Linda wrote a piece entitled “The role of deuterated detergents in NMR structure determination of membrane proteins” and is found on page 33. 
Graduate Student
BS: Chemistry, University of Pittsburgh (2007)
Dan worked with Dr. David Pratt on rotationally resolved electronic spectroscopy and Dr. Megan Spence on solid state NMR of lipid bilayer systems.
Dan’s research aims to determine the binding mechanism of opacity associated (Opa) proteins located in the membrane of Neisseria bacteria. These proteins bind to human host receptors, CEACAM and heparin sulfate proteoglycan, and induce phagocytosis of the bacteria. He will be using various nuclear magnetic resonance (NMR) experiments and isotope labeling techniques to calculate a three dimension structure of OpaI reconstituted in detergent micelles. From there he will map out the interaction between CEACAM1 and Opa.
Linda, Dan, and Brett attended Frontiers of NMR in Biology Keystone Symposium
Dan presented a poster entitled “NMR Backbone Assignment of Opa I: A mediator of host-Neisseria interactions” and Brett presented a poster entitled “Investigations towards improving solution NMR paramagnetic relaxation enhancement distance restraints for MTSSL labeled α-helical membrane proteins”. Both were invited to orally present poster previews and Dan received a travel award. The meeting was located in Big Sky, Montana and the snow was fantastic.
Brett and Dan present posters at 39th Southeastern Magnetic Resonance Conference
Brett and Dan presented posters at the 39th Southeastern Magnetic Resonance Conference (SEMRC) which was held at the University of Florida campus on October 22-24, 2010. The focus of the conference is on the exchange of ideas related to NMR-, EPR-, and MRI-based research as well as on the development of these techniques and new applications. Dan presented a poster entitled “Preparation and NMR backbone assignment of OpaI: A mediator of host Neisseria interactions”. Brett presented “Motional model of nitroxide spin label side chain dynamics on an α-helical membrane protein” and received a travel grant.
Dan wins an award at the 2010 Huskey Research Exhibition
Dan Fox received a Student Voted Top Poster in Physical Science and Mathematics for the poster he presented at the 2010 Huskey Research Exhibition.
The University of Virginia Graduate School of Arts & Sciences held the 10th Annual Robert J. Huskey Research Exhibition on April 5, 2010. Over 25 different academic programs within the Graduate School participated in oral, poster, and performance presentations. The 2010 Huskey Research Exhibition program this year featured over 110 presentations on cutting edge research in various fields.
Alison and Dan present at the Biophysical Society’s 54th Annual Meeting
Alison and Dan present at the Biophysical Society’s 54th Annual Meeting at the Moscone Convention Center in San Francisco, California, February 20-24, 2010. Dan presented a poster on the NMR structure determination of OpaI and Alison presented a talk on the molecular determinants of the spontaneous refolding of OpaI in lipid vesicles.
UVA Chemistry Colleague and Chair, David Cafiso, received a Fellow of the Biophysical Society award. 
Dan presents at the SCBB Biophysics Retreat
On January 15th, Dan Fox was invited to give a talk at the UVA Structural & Computational Biology and Biophysics Biophysics Program Retreat. He presented his progress towards the NMR structure determination of OpaI
Graduate and Undergraduate Students Present Posters at National Meetings
This last February and March,
Dan Fox presented his NMR studies of Opa proteins at the Frontiers in NMR Biology Keystone Symposium
Brett Kroncke (in photo) presented his EPR studies and Chris Reyes presented his Opa refolding and NMR studies at the 53rd Biophysical Society Meeting.
Thien Nguyen presented her mixed micelle refolding studies at the 2009 NIGMS Workshop: Enabling Technologies for Structural Biology.
