Daniel Yu


BS: Chemistry with biochemistry focus, University of Virginia (2011)

Dan is working on characterizing proteins with known structure, but unknown function. Specifically, his work focuses on TM1385 which has been annotated as a glucose-6-phosphate isomerase; however, the function has yet to be investigated experimentally. Glucose-6-phosphate isomerases are a class of enzymes involved in the glycolysis and the gluconeogenisis pathways. They interconvert fructose-6-phosphate and glucose-6-phosphate. Kinetic studies and NMR studies (in collaboration with Golda Harris) are being conducted on both the wild type and the mutated forms of TM1385 to investigate the function and mechanism of TM1385.