Publications

See PubMed or Google Scholar for full list of publications 

Imaging flow cytometry analysis of CEACAM binding to Opa-expressing Neisseria gonorrhoeae.

Werner LM*, Palmer A*, Smirnov A, Belcher-Dufrisne M, Columbus L, Criss AK

Cytometry: Part A. Online ahead of print. (2020).

CEACAM targeted liposome delivery

Kuhn J, Smirnov A, Criss AK, Columbus L

Molecular Pharmaceutics. 16:2354 - 2363 (2019). PMC6740330

Heterocellular contact can dictate arterial function.

Shu XH, Ruddiman CA, Keller TCS, Keller AS, Yang Y, Good ME, Columbus L, Best AK, and Isakson BE.

Circulation Research. 124: 1473 – 1481 (2019). PMC6540980

The fluidity of phosphocholine and maltoside micelles and the effect of CHAPS.

Kieber M, Ono T, Oliver RC, Nyenhuis, SB, Ashtari M, Tieleman DP, Columbus L

Biophysical Journal. 116:1682 – 1691 (2019). PMC6506624

Refinement of highly flexible protein structures using simulation-guided spectroscopy.

Hays JM, Kieber MK, Li JZ, Han JI, Columbus L, Kasson PM.

Angnewandte Chemistry. 57:17110 – 17114 (2018). PMC6424112  

Low q bicelles are mixed micelles.

Caldwell T*, Baoukina S*, Brock A, Oliver RC, Glover KJ, Tieleman DP, Columbus L

Journal of Physical Chemistry Letters. 9:4469 – 4473 (2018). PMC6353637

A novel conformation of the polypeptide-binding pocket supports an active substrate release from Hsp70s.

Yang J, Zong Y, Su J, Li H, Zhu H, Columbus L, Zhou L, and Liu Q.

Nature Communications 8:1201 – 1214 (2017). PMC5662698

Neisserial Opa protein – CEACAM interactions: competition for receptors as a means for bacterial invasion and pathogenesis.

Martin J, Ball L, Solomom T, Criss A, Columbus L.

Biochemistry 55: 4286 – 4294 (2016). PMC4980159

Modulating vascular hemodynamics with an alpha globin mimetic peptide (HbαX)

Keller TC, Butcher JT, Marziano C, Martin JN, Rogers S, Broseghini-Filho GB, Cabot M, Sgu X, Ning B, Best AK, Padilha AS, Purdy M, Yeager M, Peirce SM, Hu S, Doctor A, Barrett E, Le TH, Columbus L, Isakson BE.

Hypertension 68:1494 – 1503 (2016). PMC5159279

Endothelial nitric oxide synthase in the microcirculation.

Shu X*, Keller TC*, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE. 

Cellular and Molecular Life Sciences.  72:4561 – 4575 (2015). PMC4628887

Known Structure, Unknown Function: An Inquiry-based Undergraduate Biochemistry Lab Course. 

Gray C, Price CW, Lee C, Dewald A, Cline MA, McAnany CE, Columbus L, Mura C.

Biochemistry and Molecular Biology Education. 43:245 – 262 (2015). PMC4758391

Post-expression strategies for structural investigations of membrane proteins.

Columbus L.

Opinion in Structural Biology. 32: 131 – 138 (2015). PMC4512879

Solution NMR Structure Determination of polytopic α-helical membrane proteins: A guide to spin label paramagnetic relaxation enhancement restraints.

Columbus L and Kroncke B.

Methods in Enzymology. 557: 329 – 348 (2015).

Opa+ Neisseria gonorrhoeae has reduced survival in human neutrophils via Src family kinase-mediated bacterial trafficking into mature phagolysosomes.

Johnson MB, Ball LM, Daily KP, Martin JN, Columbus L, and Criss AK.

Cellular Microbiology. 17:648 – 665 (2015). PMC4402142

Tuning micelle dimensions and properties with binary surfactant mixtures.

Oliver RC, Lipfert, Fox DA, Lo RH, Kim JJ, Doniach S, Columbus L.

Langmuir.30:13353 – 13361 (2014).

Cottrell Scholars Collaborative New Faculty Workshop: Professional Development for New Chemistry Faculty.

Baker LA, Chakraverty D, Columbus L, Feig AL, Jenks WS, Pilarz M, Stains M, Waterman R, and Wesemann J.

The Journal of Chemical Education. 91: 1874-1881 (2014).

Hemoglobin α/eNOS coupling in endothelium is required for nitric oxide scavenging during vasoconstriction

Straub AC, Mutchler S, Billaud M, Mykhaylo A, Palmer L, Le TH, Somlyo AV, Columbus L, Isakson BE.

Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2594 – 2600 (2014). PMC4239174

Mapping membrane protein dynamics: a comparison of site-directed spin labeling to NMR 15N-relaxation measurements.

Lo RH, Kroncke BM, Solomon T, Columbus L.

Biophysical Journal.107:1697 – 1702 (2014). PMC4190660

The Structure of the Neisserial outer membrane protein Opa60: Loop flexibility essential to receptor recognition and bacterial engulfment.

Fox DA, Larsson P, Lo RH, Kroncke BM, Kasson P, Columbus L.

Journal of the American Chemical Society. 136:9938 – 9946 (2014). PMC4105060

Call

T: (434) 924-3241 

Follow us  

© 2020 by The Columbus Lab.

 Proudly created with Wix.com

The Columbus Lab is committed to a diverse and inclusive multidisciplinary research culture that enables lab members to obtain individual success, advance our research outcomes, and mentor and train the next generation of scientists. All members of the Columbus Lab contribute to an environment that values and respects all individuals and their unique perspectives. A scientific and laboratory culture where everyone feels they belong is our priority and critical to scientific advancement.

  • Twitter Clean