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Research in the Columbus laboratory focuses on investigating the biophysical driving forces that determine membrane protein stability, structure, dynamics, and interactions with lipids and other proteins. We are particularly interested in bacterial membrane proteins that interact with host proteins or are novel antibiotic targets. We utilize and develop many biochemical and biophysical techniques to identify and quantify these forces.

NMR

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X-ray Crystallography

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EPR

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      Imaging Flow      
        Cytometry

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SAXS

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Static and Dynamic Light Scattering

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